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News from the South African winelands

Daily news and views on South African wine. The easiest way to keep up with the latest wines and the remarkable people, places and stories behind these wines. Consumer, trade, sommelier & media focused.
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Overworked neurons burn out and fuel Parkinson’s disease

Overactivation of dopamine neurons may directly drive their death, explaining why movement-controlling brain cells degenerate in Parkinson’s. Mice with chronically stimulated neurons showed the same selective damage seen in patients, along with molecular stress responses. Targeting this overactivity could help slow disease progression.