New Research Challenges Long-Held Views About Parkinson’s Disease

Old Man Brain Parkinson's
University of Arizona researchers have discovered that levodopa-induced dyskinesia in Parkinson’s patients arises from a disconnect in the motor cortex, challenging existing views about its cause. Their study also highlights the potential of ketamine, an anesthetic, to disrupt abnormal brain patterns and promote neuroplasticity, offering promising therapeutic benefits. Credit: SciTechDaily.com

University of Arizona researchers revealed that dyskinesia in Parkinson’s patients stems from a disconnect in the motor cortex, not direct causation. Ketamine shows promise as a treatment by disrupting abnormal brain activity and promoting long-term neuroplasticity.

Researchers at the University of Arizona have provided valuable insights into one of the most common complications faced by Parkinson’s disease patients: involuntary movements that arise after prolonged treatment.

Parkinson’s disease, a neurological disorder affecting movement, occurs when DOI: 10.1093/brain/awae386

The study received funding from the National Institute of Neurological Disorders and Stroke (grants R56 NS109608 and R01 NS122805) and the Arizona Biomedical Research Commission (grant ADHS18-198846).

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